Table 3 Univariate and multivariate Cox regression hazard analyses of predictors of overall and disease-free survival
From: Emergency surgery for splenic flexure cancer: results of the SFC Study Group database
Whole sample (n = 80*) | ||||||||
|---|---|---|---|---|---|---|---|---|
Overall survival | Disease-free survival | |||||||
Variables | Univariate analysis | Multivariate analysis | Univariate analysis | Multivariate analysis | ||||
p value | HR (95% CI) | p value | Adjusted HR (95% CI) | p value | HR (95% CI) | p value | Adjusted HR (95% CI) | |
Male vs. female | 0.666 | 0.375 | ||||||
Age > 75 year | 0.493 | 0.312 | ||||||
Comorbidity > 1 | 0.742 | 0.085 | ||||||
Open vs. laparoscopic approach | 0.880 | 0.966 | ||||||
ERC vs. LC + SLC | 0.596 | 0.200 | ||||||
Synchronous metastasis | < 0.0001 | 13.37 (5.34-33.45) | < 0.0001 | 11.39 (4.46-29.11) | < 0.0001 | 23.92 (6.98-81.97) | > 0.0001 | 27.72 (7.17-87.15) |
pT4 vs. pT1-3 | 0.007 | 2.95 (1.33-6.54) | 0.046 | 2.31 (1.17-5.27) | 0.024 | 2.92 (1.15-7.44) | 0.028 | 3.04 (1.12-8.26) |
pN+ vs. pN0 | 0.146 | 0.059 | ||||||
Harvested lymph nodes < 12 | 0.814 | 0.976 | ||||||
Adjuvant chemotherapy | 0.690 | 0.111 | ||||||
Dindo-Clavien ≥ III | 0.452 | 0.411 | ||||||
Obstruction vs. perforation | 0.935 | 0.356 | ||||||