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Table 4 Laparoscopic and open cholecystectomy outcomes and 30-day post-surgery following post-propensity score matching (PSM)

From: A retrospective study of laparoscopic, robotic-assisted, and open emergent/urgent cholecystectomy based on the PINC AI Healthcare Database 2017–2020

Parameter

Laparoscopic (n = 2637)

Open (n = 2637)

p-value

Index hospitalization outcomes

 Intraoperative complications, n (%)

24 (0.9)

33 (1.3)

0.2

 Postoperative complications, n (%)

601 (23.0)

932 (35.0)

< 0.001

 Sepsis, n (%)

257 (9.7)

327 (12.0)

0.01

Gastrointestinal and digestive complications, n (%)

 Bile duct injury

8 (0.3)

11 (0.4)

0.55

 Retained gallstone

2 (< 0.1)

1 (< 0.1)

0.64

 Intestinal obstruction

86 (3.3)

208 (7.9)

< 0.001

 Gastrointestinal ulcer

5 (0.2)

20 (0.8)

0.00

 Gastrointestinal hemorrhage

16 (0.6)

25 (0.9)

0.24

Wound infection/complications, n (%)

 Surgical site infection

3 (0.1)

27 (1.0)

< 0.001

 Hemorrhage/hematoma/seroma

9 (0.3)

16 (0.6)

0.26

 Wound disruption/dehiscence

27 (1.0)

86 (3.3)

< 0.001

 Drainage of intraperitoneal abscess

4 (0.2)

68 (2.6)

< 0.001

 Blood transfusion, n (%)

147 (5.6)

372 (14.0)

< 0.001

 Pulmonary complications, n (%)

213 (8.1)

476 (18.0)

< 0.001

 Cardiovascular complications, n (%)

71 (2.7)

133 (5.0)

< 0.001

Hospital length of stay, d

< 0.001

 Mean (SD)

5.3 (4.9)

8.6 (8.0)

 

 Median (IQR)

4 (2, 7)

6 (4, 11)

 

Operating room time, min

< 0.001

 Mean (SD)

130.1 (58.9)

166.6 (72.3)

 

 Median (IQR)

120 (90, 150)

150 (120, 201)

 

30-day postoperative outcomes

 Sepsis, n (%)

295 (11.0)

394 (15.0)

< 0.001

Gastrointestinal and digestive complications, n (%)

 Bile duct injury

13 (0.5)

25 (0.9)

0.06

 Retained gallstone

2 (< 0.1)

1 (< 0.1)

0.64

 Intestinal obstruction

87 (3.3)

224 (8.5)

< 0.001

 Gastrointestinal ulcer

7 (0.3)

26 (1.0)

0.00

 Gastrointestinal hemorrhage

23 (0.9)

34 (1.3)

0.15

Wound infection/complications, n (%)

 Surgical site infection

18 (0.9)

55 (2.7)

< 0.001

 Hemorrhage/hematoma/seroma

13 (0.6)

32 (1.6)

0.01

 Wound disruption/dehiscence

40 (1.9)

104 (5.1)

< 0.001

 Drainage of intraperitoneal abscess

8 (0.4)

52 (2.5)

< 0.001

 Pulmonary complications, n (%)

225 (8.5)

503 (19.0)

< 0.001

 Cardiovascular complications, n (%)

126 (4.8)

169 (6.4)

0.01

 30-day readmission, n (%)a

209 (7.9)

292 (11.1)

< 0.001

 30-day reoperation, n (%) b

40 (1.5)

60 (2.3)

0.05

 Mortality, n (%)

50 (1.9)

133 (5.0)

< 0.001

  1. SD = Standard deviation of the mean; IQR = interquartile range
  2. aSepsis, pancreatitis, retained gallstone/biliary obstruction, renal failure, postoperative pain, pulmonary embolism, nausea/vomiting, peritoneal abscess, ileus, aspiration, postoperative seroma. Any readmission from discharge to 30-day follow-up
  3. bRetained gallstone, sepsis/infection, incisional hernia/wound disruption, bowel obstruction. Measured from scheduled OR from discharge to 30-day follow-up