Table 2 Univariate and multivariate analysis of factors related to achieve to

Gender

Male (ref)

Female

1.605

1.269

2.029

.001

–

–

–

–

Age

0.969

0.962

0.977

.001

–

–

–

–

Scores

POSSUM Physiological score

.909

.891

.928

.000

.866

.770

.974

.016

Total POSSUM

.912

.896

.929

.000

1.120

.999

1.256

.051

APACHE II SCORE

.855

.826

.884

.000

–

–

–

–

ASA score

 1 (ref.)

 2

 3

 4

 5

–

.495

.221

.055

.000

–

.347

.152

.025

.000

–

.706

.322

.121

–

–

.000

.000

.999

.999

–

171,579,770.904

99,261,356.640

53,879,330.972

26,142,808.327

–

.000

.000

.000

.000

–

–

–

–

–

.05

–

.999

.999

.999

1.000

Charlson Comorbidity Score > 6

No

Yes (ref.)

4.452

2.764

7.170

.000

–

–

–

–

Modified Frailty index

 0 (ref)

 1

 2

 3

 4

 5

 6

 7

 8

–

.488

.381

.320

.302

.188

.050

.087

.000

–

.364

.266

.203

.159

.074

.006

.010

.000

–

.656

.544

.503

.573

.481

.409

.788

–

.000

–

.000

.000

.000

.000

.000

.005

.030

1.000

–

–

–

–

Clinical data

Pulse (rpm)

0.974

.966

.982

.000

0.978

0.965

0.992

.002

Temperature °C

1.004

.987

1.020

.667

–

–

–

–

Hypertension requiring treatment

2.232

1.761

2.828

.000

2.157

1.415

3.286

.001

DM treated with insulin or oral medications

 No

 Yes (ref.)

1.885

1.408

2.524

.000

–

–

–

–

Any liver disease

 No

 Yes (ref.)

2.053

1.087

3.880

.027

–

–

–

–

Time since beginning symptoms and surgery (days)

1.002

.999

1.006

.256

–

–

–

–

Duration complaints > 72h

 No

 Yes (ref.)

1.706

1.347

2.161

.000

–

–

–

–

Palpable tender mass in the right upper abdominal quadrant

 No

 Yes (ref.)

1.538

1.210

1.954

.000

1.538

1.21

1.954

.001

Oliguria

 No

 Yes (ref.)

5.4

3.114

9.366

.000

8.319

2.253

30.714

.001

Serological tests

White blood cells > 18.000/mm3

 No

 Yes (ref.)

2.351

1.769

3.124

.000

–

–

–

–

Hemoglobin

1.004

.999

1.009

.132

–

–

–

–

Platelet count > 100,000/mm3

 No

 Yes ref

3.232

1.534

6.808

.002

–

–

–

–

INR > 1.5

 No

 Yes (ref.)

4.840

2.942

7.964

.000

–

–

–

–

Creatinine > 2mg/dL

 No

 Yes (ref.)

6.132

3.610

10.419

.000

4.331

1.272

14.748

.019

Increased total bilirubin > 2 mg/dL?

 No

 Yes (ref.)

3.004

2.210

4.083

.000

–

–

–

–

Data about AC

Previous percutaneous cholecystostomy

 No

 Yes (ref.)

5.944

2.529

13.969

.000

6.603

1.734

25.148

.006

Associated Common Bile Duct Stones (confirmed by EUS or MRI

 No

 Yes (ref.)

3.664

2.185

6.145

.000

3.954

1.681

9.300

.002

Gangrenous cholecystitis

 No

 Yes (ref.)

2.594

2.006

3.354

.000

1.733

1.086

2.765

.021

Pericholecystic abscess

 No

 Yes (ref.)

3.918

2.743

5.595

.000

3.001

1.501

5.998

.002

Hepatic abscess

 No

 Yes (ref.)

9.780

3.739

25.582

.000

–

–

–

–

Biliary peritonitis

 No

 Yes (ref.)

3.545

1.983

6.338

.000

–

–

–

–

ACC grade

 1

 2

 3 (ref.)

.443

.000

–

.340

.000

–

.578

–

–

.000

.999

–

–

–

–

–

*Operative time in min

.988

.985

.991

.000

.994

.990

.998

.007

Bail out procedure?

 No

 Yes (ref.)

6.674

4.194

10.621

.000

–

–

–

–

Chole-Risk score

 0 (ref.)

 1

 2

 3

 4

.715

.483

.151

.039

.505

.333

.089

.005

1.012

.701

.258

.315

.000

–

.058

.000

.000

.002

–

–

–

–

POSSUM Operative severity score

  < 15

  > 15 (ref)

12.137

5.434

27.110

.000

8.453

2.073

34.462

.003